Inositol phosphates are crucial secondary messengers that modulate a wide range of cellular processes, from energy metabolism to gene expression. These molecules, particularly inositol pyrophosphates, ...

A newly discovered pair of stem cell lineages drives the formation of both tooth roots and the bone that anchors them. Understanding how these cells switch roles could pave the way for regenerating ...

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

SMART, a new software package, can make studying signaling processes significantly easier. Results could accelerate research in fields across the life sciences, such as systems biology, pharmacology ...

A study shows that high levels of negatively charged lipids can lock growth receptors into an overactive state, driving ...

Within the expanding domain of short-chain bioactive peptides, Decapeptide-12 has emerged as a particularly intriguing molecular construct.

Fluorescent probes have transformed modern biology by allowing researchers to tag and visualize individual molecules in ...

Scientists at The Wistar Institute and clinical researchers from ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a vulnerability in pancreatic cancer that could be ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...

B cells are white blood cells that form a core part of the body's adaptive immune system, enabling it to recognize specific ...