Nature

Efficient discovery of single-nucleotide polymorphisms in coding regions of human genes

Most high-throughput SNP discovery has been from bulk genomic sequence. However, because coding regions constitute only a small fraction of the human genome, the fraction of these data that are cSNPs ...
Nature

Effects of protein coding polymorphisms in the kallikrein 1 gene on baseline blood pressure and antihypertensive response to irbesartan in Chinese hypertensive patients

The KLK1 has a critical role in the cardioprotective effect of ACE inhibitors in acute myocardial ischaemia. 20 Genetically engineered mice deficient in the KLK1 and kinin confirm the role of the KLK1 ...
ascopubs.org

A polymorphism in the coding sequence of WT1 is an independent prognostic marker in 1,101 patients with lobular breast cancer.

Clinical relevance of mesenchymal stem cell–induced resistance to chemotherapy. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does not include a full text ...
Healio

Polymorphisms in gene coding for VEGF receptor site may up AMD risk

Evidence from genotyping studies continues to suggest that genetics plays a strong role in the development of age-related macular degeneration. According to a study that enrolled 226 patients with AMD ...