ascopubs.org

Safety, Feasibility, and Patient Experience of Ten-Minute Pembrolizumab Infusions: A Prospective Cohort Study

What is on the Horizon Beyond Platinum and Immunotherapy for Patients With Advanced Non–Small Cell Lung Cancer Without Actionable Genomic Aberrations? In this prospective single-center study at a ...
BMJ

Device-measured physical activity, sedentary time, and risk of all-cause mortality: an individual participant data analysis of four prospective cohort studies

Objectives To examine whether moderate-to-vigorous physical activity (MVPA) modifies the association between sedentary time and mortality and vice versa, and estimate the joint associations of MVPA ...
ascopubs.org

Using Dose-Escalation and -Expansion Cohort Study as Pivotal Trial for Targeted Anticancer Drug Approval

BRCA1-Associated Protein 1 and Enhancer of Zeste Homolog 2: Pathway Interaction and Therapeutic Intervention in Breast Cancer, Mesothelioma, and Lymphoma Early-phase clinical trials (EPCTs) have been ...
Medscape

The Entire Disease Continuum: The Potential of Long-Term Study Cohorts

Lung development and function is notoriously difficult to study. Both are affected by a range of environmental factors, such as first- and second-hand smoke, air pollution, and infections and genetic ...