These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

Researchers report a new way to turn off the harmful immune attack that occurs during autoimmune diseases such as multiple sclerosis (MS), while keeping healthy functions of the immune system intact.

A recent paper in Nature Biomedical Engineering, by Dr. David J. Mooney demonstrated how a new vaccine can enhance and maintain lymph node function to boost immunity against cancer in mice. Mooney, a ...

Dramatic changes in lymphatic vessel contraction and in the lymph nodes that drain inflamed joints are associated with disease progression and response to therapy in murine models of rheumatoid ...

Lymph nodes are a key part of the human immune system, whose primary function is to combat infections. The effectiveness of vaccines is based on their ability to trigger events in lymph nodes that ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...

Vaccines trigger a notably rapid response in the stromal cells of draining lymph nodes within the first hours after administration. Researchers at the University of Turku and the InFLAMES Flagship in ...

Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host ...

The research group of prof. Sanjiv Luther at the department of immunobiology of the University of Lausanne has discovered that a fibroblast subtype is essential for coordinating certain immune cells ...

Lymph nodes are small, bean-shaped glands throughout the body. They are part of the lymph system, which carries fluid (lymph fluid), nutrients, and waste material between the body tissues and the ...