A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human brain development before birth—a resource that resolves longstanding ...

In a new study from Karolinska Institutet, published in Nature Neuroscience, researchers have identified the neurogenic progenitor that gives rise to dopaminergic neurons, the primary neurons affected ...

Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

Leuven, 7 August 2024—The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU ...

The human brain is made up of billions of nerve cells (neurons) that communicate with each other in vast, interconnected networks. For the brain to function reliably, there must be a fine balance ...

The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU Leuven Center for ...

This is a useful study that seeks to elucidate the molecular mechanisms underlying spinal motor circuit assembly. The authors demonstrate that loss of Onecut transcription factors in spinal motor ...

A baby's neuronal development can be compromised by infections in utero Source: Peter Oslanec/Unsplash It goes without saying that the health of a pregnant mother and the conditions inside the womb ...