Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Normally, cells must be lysed for a so-called transcriptome analysis - which reveals which genes are currently being ...

The advent of single-cell omics technologies has revolutionized our understanding of the complex cellular landscape in cancer. Traditional bulk sequencing ...

Scientists at St. Jude Children's Research Hospital, the National Center for Genomic Analysis and the University of Adelaide have created a single-cell RNA analysis method that is 47 times cheaper and ...

Head and neck cancers display notable heterogeneity in their immune cell infiltrates, which reflect intricate spatial arrangements and dynamic networks of ...

VIB-VUB researchers have developed a patient-relevant lung adenocarcinoma model combined with SEPARATE-Seq technology to ...

While such advances bring with them a breadth of knowledge, the immense complexity of the datasets makes it challenging for scientists to analyze them using current computational methods. Now, ...