A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more ...

Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Chang leads assay and applications development at Takara Bio, driving the commercialization of novel spatial genomics products. She has extensive experience in single-cell multiomics technologies and ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries ...

Andreas Pfenning discusses the techniques being developed and used to study neuronal heterogeneity and the therapeutic potential of his work.