As a fast and easy-to-use gene-editing technique, CRISPR is one of the biggest discoveries in 21 st century medical science, and an important facilitator of gene therapy development. Several gene ...
Researchers introduce Variant-aware Cas-OFFinder, a web-based tool that improves CRISPR off-target predictions by incorporating individual genetic differences. By reconstructing allele-specific ...
This review summarizes the current landscape of ADC development, focusing on target selection and adverse impacts. It will guide future research to optimize the efficacy and safety of ADCs. ADCs are a ...
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