Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on mutation processes that contribute to cancer and inherited genetic conditions ...

Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

The study, by Dr Greg Ngo and Professor Duncan Baird from Cardiff University’s School of Medicine, reveals the mechanism behind chromoanasynthesis, a catastrophic type of chromosome rearrangement that ...

The Y chromosome is among the smallest in the human body and carries the fewest genes. Researchers are paying renewed attention to its role in cancer—specifically, what happens when it vanishes.

The loss of the Y chromosome in tumour cells is linked to poor outcomes for people with cancer 1, but this genetic alteration might also compromise immune cells that would otherwise fight the disease.

Sharks and rays have been found to have an XY sex chromosome system superficially like our own, but with its own unique features. It’s also older than that of any other vertebrate. There are lots of ...

Researchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a ...

Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises - shedding new light on mutation processes that ...