This Scientific Reports Collection welcomes original research on Metabolic reprogramming in immune-mediated disorders. Narrative review articles are also welcomed, to our sister journal Scientific ...

Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, ...

Panakeia ("the Company"), the world's first in silico multi-omics company, today unveiled landmark pathway activation data in cancers at the American Association for Cancer Research (AACR) Annual ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

A recent study has demonstrated the power of metabolic engineering in enhancing the antitumor activity of chimeric antigen ...

Therapeutic fasting offers a metabolic approach to chronic pain by shifting to fat metabolism, reducing systemic inflammation ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer—and how restoring their ...

Scientists have discovered a way to supercharge the immune system’s T cells by blocking a protein called Ant2, forcing the cells to rewire how they generate energy. This shift makes them more powerful ...

New study reveals metabolic remodeling as an early event in diastolic dysfunction Restrictive cardiomyopathy (RCM) caused by ...

Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company, today announced positive data from its HT-VA study, conducted under its Cooperative Research and Development ...