In this collection we highlight a wide range of spatial imaging and spatial omics approaches that enable the spatial visualization of molecular targets in biological tissue. The protocols span between ...

Scope-X, an expanded version of the Seq-Scope spatial transcriptomics method. The technique overcomes diffusion limits and enables higher-resolution mapping of mRNA within cells.

The Whole Transcriptome Panel for Bruker’s CosMx Spatial Molecular Imager (SMI) represents a breakthrough in spatial biology. With the ability to detect and quantify over 18,000 RNA transcripts at ...

This research project seeks to address the challenging problem of sharpening remotely sensed hyperspectral imagery with higher resolution multispectral or panchromatic imagery, with a focus on ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Spatial proteomics is a spatial biology method that helps study the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular ...

Photothermal AFM-IR technology provides spatially resolved infrared spectroscopy for detailed compositional mapping of ...