INSTALL results showed successful and safe non-viral insertion of large genetic payloads in the livers of mice when delivered by lipid nanoparticles (LNPs). In contrast, mice experienced fatal immune ...

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life reconstructions ever created. Using computer technology, scientists have ...

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people, are now at the center of a much larger medical revolution. Researchers ...

Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells.